Core/Unit Introduction

がん進展制御研究コア

Cancer Stem Cell Research Unit

Elucidation of the mechanism of cancer stem cells, clinical application and drug development

Specialty:cancer cancer medical science

Keyword:cancer cancer stem cell metabolism of cancer drugs targeting cancer molecules

/ Professor
Cancer Research Institute

TAKAHASHI Chiaki

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Cancer Research Institute

KASAHARA Atsuko

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Research Content

The most important cell in a cancer is the cancer stem cell. Even if 99.9% of cancer cells are killed by anti-cancer agents, 0.1% cancer cells, i.e., cancer stem cells, survive, grow and form a colony after metastasis. This is the reason why cancer stem cells are essential in metastasis, recurrence and resistance against anti-cancer agents. This Research Unit aims to elucidate the mechanisms of cancer generation and progression, and to develop new treatments, by studying normal stem cells and cancer stem cells as well as cancer stem cells from solid tumors and from hematopoietic tumors on the same platform. We expect to obtain special research outcomes that give much impact on this research area. Furthermore, we promote cooperation and collaboration with academia and industry, which should train young researchers capable of coping with the various needs of research and development.